Reduced local immune response with continuous positive airway pressure during one-lung ventilation for oesophagectomy

Reduced local immune response with continuous positive airway pressure during one-lung ventilation for oesophagectomy.

BACKGROUND Transthoracic oesophagectomy requires prolonged one-lung ventilation causing systemic and local inflammatory responses. Application of continuous positive airway pressure (CPAP) to the collapsed lung potentially reduces pulmonary damage, hypoxia, and consequent inflammation. This randomized controlled trial studied the influence of CPAP applied to the collapsed right lung during thor...

RESPIRATION AND THE AIRWAY Reduced local immune response with continuous positive airway pressure during one-lung ventilation for oesophagectomy

Editor’s key points † One-lung ventilation can cause local and systemic inflammatory responses. † In this study of patients undergoing oesophagectomy, cytokine concentrations in broncho-alveolar lavage fluid were lower in patients receiving CPAP to the collapsed lung. † There were no differences in systemic concentrations of inflammatory markers or clinical outcomes. † Furtherdata are required ...

Role of continuous positive airway pressure to the non-ventilated lung during one-lung ventilation with low tidal volumes

INTRODUCTION In multiple study populations large tidal volumes (8 - 12 ml/kg) have deleterious effects on lung function in multiple study populations. The accepted approach to hypoxemia during one-lung ventilation is the application of continuous positive airway pressure to the non-ventilated lung first, followed by application of positive end-expiratory pressure to the ventilated lung. To our ...

A Comparative Study of Treatment Response of Respiratory Distress Syndrome in Preterm Infants: Early Nasal Intermittent Positive Pressure Ventilation versus Early Nasal Continuous Positive Airway Pressure

Background Infant respiratory distress syndrome (IRDS) is one of the main causes of serious complications and death in preterm infants. Both Nasal Continuous Positive Airway Pressure (NCPAP) and Nasal Intermittent Positive Pressure Ventilation (NIPPV) are known as the most common treatment strategies for IRDS. The present study intended to compare NCPAP and NIPPV in the treatment of preterm inf...

Intraocular Pressure during Continuous Positive Airway Pressure